While the original film focused on a young man (Ephrem) who joins a secret group called the "FBI" and navigates a romantic dilemma with a woman named Afyam, FBI 2 escalates the physical comedy and situational humor. The story follows the main characters through a series of misunderstandings and amateur "espionage" missions, often parodying tropes found in Hollywood action films but set within the local context of Addis Ababa.